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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T73224 AMPK-IN-1

AMPK-IN-1 是一种 AMPK 激活剂 (对亚型α2β2γ1的 EC50为 551 nM)。AMPK-IN-1 可导致 eEF2 的 mTORC1-非依赖性磷酸化。
T83125 AMPK-α1β1γ1 activator 1

AMPK Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
AMPK-α1β1γ1激活剂1 (M1) 是一个衍生于Indole-3-carcinoma的酰基葡萄糖醛酸代谢AMPK激活剂,专一性地针对人类β1亚型,表现出38.1nM的EC50值。该化合物能够直接结合至人AMPK α1β1γ1亚型,适用于糖尿病肾病的相关研究。
T79649 CB1R/AMPK modulator 1

Cannabinoid Receptor GPCR/G Protein
CB1R/AMPK modulator 1 (Compound 38-S)为一种口服活性CB1R/AMPK调节剂,具有0.81 nM的Ki及3.9 nM的CB1R IC50。该化合物能够激活AMPK,且能降低食物摄入量和体重,同时改善葡萄糖耐量与胰岛素敏感性。

化合物

AMPK-IN-1
Cat.No: T73224
Synonym:
Target:
AMPK-α1β1γ1 activator 1
Cat.No: T83125
Synonym:
Target: AMPK
CB1R/AMPK modulator 1
Cat.No: T79649
Synonym:
Target: Cannabinoid Receptor
Cat. No. Product Name Species Expression System
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

AMPK, AMPK(α1, ...

Human Baculovirus Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-04452 AMPK (G1/B2/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

AMPK, AMPK(α1, ...

Human Baculovirus Insect Cells
AMPK (G1/B2/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619&O43741&Q13131-1.
TMPY-04454 AMPK (G1/B1/A2) Heterotrimer Protein, Human, Recombinant (His & GST)

AMPK, AMPK(α2, β1

Human Baculovirus Insect Cells
AMPK (G1/B1/A2) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 158 kDa and the accession number is P54619&O43741&P54646.
TMPY-04453 AMPK (G1/B2/A2) Heterotrimer Protein, Human, Recombinant (His & GST)

AMPK, AMPK(α2, β2, γ...

Human Baculovirus Insect Cells
AMPK (G1/B2/A2) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 158 kDa and the accession number is P54619&Q9Y478&P54646.
TMPK-01522 Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)

RMF,WT33,WIT-2,MHC,WAGR,AWT1,GUD,WT1,NPHS4GUD

Human & Mouse HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and RMFPNAPYL peptide of  the WT-1.
TMPK-01535 Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)

Macropain chain 7,LMP2,Proteasome chain 7,RING12,PSMB9,MHC,R...

Human & Mouse HEK293 Cells
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPK-01523 Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi)

WAGR,WT33,AWT1,GUD,RMF,WT1,WIT-2,MHC,NPHS4GUD

Human & Mouse HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and RMFPNAPYL peptide of  the WT-1.
TMPK-01534 Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)

RING12,PSMB9,Proteasome chain 7,RMF,LMP-2,LMP2,MHC,Macropain...

Human & Mouse HEK293 Cells
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...

重组蛋白

AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04451
Species: Human
Expression System: Baculovirus Insect Cells
AMPK (G1/B2/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04452
Species: Human
Expression System: Baculovirus Insect Cells
AMPK (G1/B1/A2) Heterotrimer Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04454
Species: Human
Expression System: Baculovirus Insect Cells
AMPK (G1/B2/A2) Heterotrimer Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04453
Species: Human
Expression System: Baculovirus Insect Cells
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01522
Species: Human & Mouse
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01535
Species: Human & Mouse
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01523
Species: Human & Mouse
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01534
Species: Human & Mouse
Expression System: HEK293 Cells
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